Product Description Polyquaternium-1 is a very safe preservative, which shows very low acute toxicity in rats.Polyquaternium-1 is slightly toxic orally (LD50> 4.47 ml/l at 40% active in rats). Polyquaternium-1 is not irritating to skin at 40%. The product is not a skin sensitizer and is non-mutagenic. Polyquaternium-1 is a detergent-type preservative derived from,also named as Polidronium Chloride,PQ-1.Polyquaternium-1 is formulated in the mid of 1980s as a preservative for contact lens storage solutions.Nowadays,it is being increasingly used as a presverative in ophthalmic drops for glaucoma, artificial tear solutions and top cosmetic formuations. Polyquaternium-1 is a cationic polymer prepared by the controlled polymerization of dimethylamine and bis-dichlorobutene, end capped with tris-b-Hydroxyethylamine. BASIC ANALYSIS item value CAS No. 75345-27-6 Other Names POLYQUATERNIUM-1 MF C33H70N5O6X2.5Cl Place of Origin China Purity 99 Model Number 75345-27-6 Application Syntheses Material Intermediates Appearance White crystalline powder Molecular Weight 810.21 Function This product is a high polymer cationic surfactant, which is highly soluble with cationic, non-ionic and amphoteric surfactants.